The studio I rehearse at has an Ampeg 8x10 in all of the rooms excluding one. The other room has a EBS 4x10 and the EBS blew the Ampeg out the water in every aspect. Just sounded louder, clearer, beefier, tighter and many other words ending in 'er'.
This was also using a class D amp head. Plenty of oomph!
I suppose it depends what you like. I definitely don't go for a 'vintage' type sound.