Yup, as suggested above the end result is down to personal taste. Works a treat for me, among my various cab combinations.
As long as half the amp power - 250W - isn't overpowering either cab you're ok on a technical level. Looking at your OP I'd give it a try.
Something else to be aware of, especially if using different brands of cab, is phase.. if you start with your 212 sounding great, then adding the 112 makes your sound seem somewhat lacking, the cabs could well be 'out of phase' i.e. speakers travelling in opposite directions. Easy to remedy just by reversing the polarity of one of the cables.