[quote name='DiMarco' timestamp='1346275760' post='1787501']
Here's my opinion.
The multi effect modeling toys are nice for quickly recording ideas on your laptop computer. Real handy for this.
They do however ALL kill some of your instrument's signature tone and certainly do NOT stack up to using a bunch of proper analog stompboxes plus a real tube comp.
Gawd knows I have tried so many of them. Owned and own Line6, Digitech, Boss and TC Electronic multi effect and modeling units. Never used any of them in live situations.
For guitar as well, the Boss GT-8 is in the bottom drawer in storage and I'm using an AMT SS-11 tube guitar preamp with a holygrail reverb (AMT stompbox with its own fx loop, how cool is that?) instead.
Long story short: multi fx units are tone killers.
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I'm not so sure about them being "tone killers"? If Pantherairsoft is willing to replace the majority of his massai board of quality stomps for a M13, then I think he would take that into account.
I've only had a couple of multi fx units & now have a small selection of stomps, but I can't say I noticed a loss of tone when I was playing live.