I'm using a classic Stingray c/w Aguilar TH500 & 2 SL112 cabs, playing classic rock.
Tend to max out bass on guitar and have treble about +2. On the amp I cut the lower mids, boost bass and have treble at 0.
I find this sound really cuts through especially across all the string and up the neck, also it gives a big fat bottom end to our sound, which is also well defined owing to the Gramma Pad on which the rig sits. Hope this helps.
ATB Paul.