The answer to your question is, yes, it is down to trial and error. But DB strings a very expensive to just try and find out you don't like them.
Are you using a magnetic or bridge pickup. That will dictate what core you have in a string. Synthetic core strings will not work with mag pickups.
I use Flexocor strings on my NS CR. Lovely sound and as close to a DB with an EUB. I have also used Belcantos, just as good.
There are some sound samples of different DB strings in this link.
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