Other than wood choices or neck profiles etc, I don't think many custom builders offer much you can't get from the big companies with careful consideration (in terms of sound at least). I think 'handmade' is over hyped, to me it just means it took longer and hence cost more.
Technology does indeed save money, and i'd say a PLEK machine is more precise than a luthier. The difference is on quality control of mass producers, not the technology. When you find a big maker than has high QC (cough Lakland cough) then there is nothing better than a very well made bass at a reasonable price.
I've started moving away from the US made principle as some of what coming out of the far east at the moment is as good in quality but a lot cheaper. Other examples are G&L Tribute, Squier, Sterling by Musicman etc.