[quote name='Kev' timestamp='1373125353' post='2133986']
Boss pedals have good buffers so tone loss or volume loss would not be expected, what you are describing for the pedals you have isn't right.
Laborious, but you should check each pedal individually against their bypass and the direct to amp tone, a loop switch would be best to test this for easy comparison.
[/quote]
I agree with the second statement, but the decoupling capacitor at the input of each buffered pedal will shave a little bit off the bottom end, and by the time this has happened several times, you can expect a significant loss of bass.
Damon, once you have worked out which pedals are the worst culprits (try them in groups of 2 or 3 as well as individually), I suggest you look to true-bypass these with something like the [url="http://www.thegigrig.com/acatalog/Loopy2-301.html#SID=13"]Loopy-2[/url] or [url="http://www.thegigrig.com/acatalog/QuarterMasterhome.html#SID=1"]Quartermaster[/url] from [url="http://www.thegigrig.com/"]TheGigRig[/url]. I also recommend leaving the best buffered pedal connected near the front of the signal chain, as it will happily drive the next pedal or a long cable run to your amp.