As far as I’m aware it does make a difference. Better quality loaders have more memory for longer and more detailed / higher resolution responses.
Whether that detail can be heard or not is another thing.
I know he recently did a bass version of the Warlow which is a Muff style pedal. It has many of the internal options you mention here. Clean bypass with bass boost.
that’s how I use mine. Always on and first in the chain. Just adds a little gain. After a while you won’t notice it at all unless you turn it off. I mean that in a good way of course.
Anyone seen them this weekend or tonight in London. I was at Manchester. Incredible. What a performance. What a bassist. The sound was very loud but really good quality. Proper HiFi 👌