To be fair, and I know this is not gospel, but I don't often play up beyond the 12th on the low E. I does sound a bit weird, and your hand will feel uncomfortable that high up on the low E.
And please everyone, I know it is possible to play up there, but I have no idea of the OP's playing ability. I just know that I am a bass teacher, and that while I can do it, I know it takes alot of practice and experience for it to be natural.
I would be interested to know how it feels between 3rd and, say, 7th fret.