I find I tend not to worry about touching my amp, I used to worry a lot about trying to get the right tone for each song, found i was tap dancing / knob twiddling too much on songs.
Which was counter productive as you want no more than 3-4 seconds between songs.
My setlist is pretty varied but my method is as follows.
I use a passive J so perhaps for your gig's keep it simple and go for a bass mid and treble all on the zero or / centre detente just change your sound with pickup blend.
1. Find a good tone for the stage/play area and set my amp a little louder than I need.
2. Roll my pickups to about 70% , along with my tone to about 50% , this is my default rock tone, i use a 70's spaced Jazz so its a bit clankier than most.
also i've got a bit of easy headroom for when the guitarists seem to creep a bit higher
3. Use effects only on songs that REALLY need them, uptown funk, ( synth part)
4 Otherwise just adjust my pickup balance ( volume controls for me) / play position or technique pick , fingers or for motown stuff i've even been known to thumb pluck palm mute