Here’s my 2p… I have small hands, so I notice the difference. I’m not saying it’s unplayable for me, but running scales/arpeggios for long periods, my fretting hand fatigues much quicker on a 35” scale.
the 35” defo has a tighter B, but my 34” ns5crfm now has a slightly larger gauge B string which certainly helps to tighten things up a little.