Yes, seriously: if you do nothing to change the sound, you'll already have tubey, fatty sound.
From there, EQ all you like, as it never becomes modern and Hi-Fi.
Change the tubes mainly for different gain levels.
Right now I'm having fun with a new Qsiure CV '50s P with factory strings (easy on the fingers, but seem deadish), and with a sad face on the EQ (though admittedly the sad face is hard to see with those round knobs - and so few of them too!)
In addition, I'm very active at moving my playing hand between the neck and the bridge to press out some treble occasionally.
Enjoy your new amp!
best,
bert