Just wanted to give an uncharacteristic plug. It was new string time and i've been playing in Drop C quite a lot lately so I was gonna get some heavy gauge high-beams, but came across these instead, so I bought a pack of these in my regular gauge (0.045-0.105).
They claim they're specially engineered or some such to provide better intonation and tension when detuning. I was a tad skeptical, but I'm glad I bought them. The intonation difference is noticeable, quick fret changes on the low C and G are a lot less muddy, but the main selling point for me is the feel, they somehow maintain pretty much the same tension in any tuning, I used to hate the slackness of playing in Drop C, and I used to get a lot of fret buzz, no more. They also stay in tuning magnificently, with my old strings I'd have to retune the low C every 5 minutes for a while until it kept it's tuning, not with these, tuned up once after I restrung and haven't had to do it since.
If you drop tune, you need these strings. That is all.