If you need more effects than drive, I'd get a Line6 Pod go. Easier to use than the Helix, but with its effects. Great sounding unit. I've seen some people using the TC Electronic multi with great results.
If you just need two drives/fuzz, I'd get a Source Audio Aftershock. You can use it as a two channel overdrive pedal, but it has memory for more. The Ashdown NM2 is also a two-channel overdrive/distortion. For overdrive and fuzz, the Way Huge Pork and Pickle also sounds awesome.