Let me summarise the way of getting positive outcomes -
1. PA does all the heavy lifting
2. Onstage volume as low as possible or even better... silent stage. All this reduces the chance of feedback and unwanted bleed into mics
3. Yes, I know all your favourite artists use big amps on stage... but they also tend to play on big stages, reducing the bleed. 2 in a pub (for example... or difficult venue (highly reflective surfaces)) is a winning move.
4. IEMs can be used in the pub as well as stadiums. Arguably they will be more useful in a pub for creating a better sound that is easier to mix out front... and easier for yourself to hear at a safer volume.
5. If you are using monitors, make sure they are pointing up at you from the floor (or roof mounted (as in some venues) pointing down). Depending upon the mic pickup pattern, either behind the mic of off to the sides of the read of the mic.
Regarding 2 and 3... Springsteen knows best -
His backline is big - but so is his stage - so separation between volume sources and mics are maximised - leading to a greater reduction in chance of feedback. The amps and cabs are running enough to get whatever tone guitarists tend to be precious of. They are still miced up and the PA is providing the volume for FoH. The cabs are completely off axis to the mics in the fact that they are pointing straight up - greatly minimising bleed.
Oh and 6. If your drummer is a noisy f**k, your band may sound better for them using an elec kit. (OK tonally may not sound as good... but a decent mix is superior to overly powerful drums in the mix with a load of cymbal bleed going into the open mics). If not, drum screen/booth of shame (although practically of moving this can be prohibitive. Just get the noisy buggers to shut up a bit (they won't... they may for sound check... but they'll always do the equivalent of the guitarist turning around and turning up (e.g. hitting harder) anyway)