Just to chip in my 5p's worth. My first experience of playing 5 sting was an Ibanez SR505. I loved the range and the approach and the neck was lovely and slim and fast which suited my small-ish hands, but I found it too difficult to play with a pick or to slap so I went the other way when I though "okay, I'm really into this, gonna go all-in" and got a Dingwall Combustion. Sometimes it is a bit of a challenge, either at near the first or 24th frets but to me it's mainly a technique thing. I mean, check this out:
https://www.facebook.com/watch/?v=183742793618209
Not saying comfort's not something to consider but I was happy to learn to adapt to a wide string spacing and a long neck in exchange for a saleable, pickable bass.