i have a stack of glockenklang cabinets (quadro and duo) and of orange cabinets (obc410 and 115) aswell. the orange sounds completly different with these. with the glock cabinets is sounds very hifi, lots of fat bass and crisp highs, almost like a solid state amp, whereas with the orange cabinets there is also very much bottom but also lots of mids and gritt. much less top end.
i like both and can´t say which i like more. the orange cabinets suit perfect for rock´n roll but are somewhat limited, especially if you play a passive bass since the eq on the orange top is somewhat limited. it´s a bit like a one-trick-pony, but what a trick! if i need a versatile sound for cover music i go with the glockenklang cabinets.
i´d try it with the mesa cabinet of yours, maybe it´s the golden middle.