Absolutely this. The best 5 string I've ever owned was a 34" Warwick Thumb. The B string was a 125 tapered Sadowsky. Complete tonal authority, with none of the usual leap in note integrity when playing across the B and E string.
In my experience a really heavy B string just results in ill-focused whumph, but playing styles should be taken into consideration - if you pluck lightly down by the bridge you're likely to have a very different response to someone playing hard with a pick or aggressive fingerstyle.