[quote name='Mr. Foxen' timestamp='1342380530' post='1734101']
Not so much the gauge at issue as the tension, what tuning are you using those in? Also the bridge would be more of a concern than the neck. Both the bridge creeping under tension and getting tail lift, and fitting the large strings through the holes.
[/quote]
I play in two tunings, one consisting of A G C F and the other A# F A# D#
I have both of my Fender Jazz basses set up for these tunings, had to have my nuts (no pun intended) slightly widened to accommodate the strings.
My guitarist would like to play in even lower but I told humid won't, lol